Wei Hong Yeo

Wei Hong Yeo

Ph.D. Candidate at Northwestern University

Publications

Physically informed Monte Carlo simulation of dual-wedge prism-based spectroscopic single-molecule localization microscopy

Published in Journal of Biomedical Optics, 2023

This paper combines spectroscopic single-molecule localization microscopy (SMLM) with a Monte Carlo (MC) simulation to effectively model the imaging process with a dual-wedge prism (DWP), enabling us to better optimize our experimental setups for improved spectroscopic performance.

Recommended citation: Wei-Hong Yeo, Cheng Sun, Hao F. Zhang (2023). Physically informed Monte Carlo simulation of dual-wedge prism-based spectroscopic single-molecule localization microscopy. Journal of Biomedical Optics. https://doi.org/10.1117/1.JBO.29.S1.S11502

Investigating uncertainties in single-molecule localization microscopy using experimentally informed Monte-Carlo simulation

Published in Nano Letters, 2023

This paper combines single-molecule localization microscopy (SMLM) with a Monte Carlo (MC) simulation to effectively model the labeling uncertainties of the nuclear pore complex (NPC), enhancing the interpretation of SMLM images and deepening our understanding of cellular substructures.

Recommended citation: Wei-Hong Yeo, Yang Zhang, Amy E. Neely, Xiaomin Bao, Cheng Sun, Hao F. Zhang (2023). Investigating uncertainties in single-molecule localization microscopy using experimentally informed Monte-Carlo simulation. Nano Letters, 23(16), 7253-7259. https://doi.org/10.1021/acs.nanolett.3c00852

Monolithic dual-wedge prism-based spectroscopic single-molecule localization microscopy

Published in Nanophotonics, 2022

This paper introduces a dual-wedge prism-based monolithic imaging spectrometer for spectroscopic single-molecule localization microscopy (sSMLM), which offers improved performance and feasibility compared to traditional grating-based methods.

Recommended citation: Ki-Hee Song, Benjamin Brenner, Wei-Hong Yeo, Junghun Kweon, Zhen Cai, Yang Zhang, Youngseop Lee, Xusan Yang, Cheng Sun, Hao F. Zhang (2022). Monolithic dual-wedge prism-based spectroscopic single-molecule localization microscopy. Nanophotonics, 11(8), 1527–1535. https://doi.org/10.1515/nanoph-2021-0541